An integrated epigenetic and genetic approach to common human disease.

@article{Bjornsson2004AnIE,
  title={An integrated epigenetic and genetic approach to common human disease.},
  author={Hans T Bjornsson and M Daniele Fallin and Andrew P. Feinberg},
  journal={Trends in genetics : TIG},
  year={2004},
  volume={20 8},
  pages={
          350-8
        }
}
Epigenetic information is heritable during cell division but is not contained within the DNA sequence itself. Despite increasing evidence for and interest in the role of epigenetics in human disease, particularly in cancer, virtually no epigenetic information is routinely or systematically measured at the genome level. The current population-based approach to common disease relates common DNA sequence variants to either disease status or incremental quantitative traits contributing to disease… CONTINUE READING

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