An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids.

@article{Srinivasan2004AnID,
  title={An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids.},
  author={Vijay Srinivasan and Vamsee K. Pamula and Richard B. Fair},
  journal={Lab on a chip},
  year={2004},
  volume={4 4},
  pages={310-5}
}
Clinical diagnostics is one of the most promising applications for microfluidic lab-on-a-chip systems, especially in a point-of-care setting. Conventional microfluidic devices are usually based on continuous-flow in microchannels, and offer little flexibility in terms of reconfigurability and scalability. Handling of real physiological samples has also been a major challenge in these devices. We present an alternative paradigm--a fully integrated and reconfigurable droplet-based "digital… CONTINUE READING
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