An insulin receptor gene polymorphism is associated with diastolic blood pressure in Chinese subjects with components of the metabolic syndrome.

@article{Thomas2000AnIR,
  title={An insulin receptor gene polymorphism is associated with diastolic blood pressure in Chinese subjects with components of the metabolic syndrome.},
  author={G Neil Thomas and Brian Tomlinson and Juliana C. Chan and Zoe S K Lee and C S Cockran and Julian A.J.H. Critchley},
  journal={American journal of hypertension},
  year={2000},
  volume={13 7},
  pages={745-52}
}
Insulin resistance has been described as a possible underlying link for the clustering of Type 2 diabetes mellitus, hypertension, obesity, and dyslipidemia, known as the metabolic syndrome. Mutations within the insulin receptor have been associated with hypertension in some white and Oriental populations. We examined the relationship between the insulin receptor NsiI restriction fragment-length polymorphism (RFLP) and biochemical and anthropometric parameters associated with these disorders in… CONTINUE READING

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