An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti.

@article{Brown2008AnIP,
  title={An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti.},
  author={Mark R. Brown and Kevin D. Clark and Monika Gulia and Zhangwu Zhao and Stephen F. Garczynski and Joe W. Crim and Richard J Suderman and Michael R Strand},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 15},
  pages={5716-21}
}
Ingestion of vertebrate blood is essential for egg maturation and transmission of disease-causing parasites by female mosquitoes. Prior studies with the yellow fever mosquito, Aedes aegypti, indicated blood feeding stimulates egg production by triggering the release of hormones from medial neurosecretory cells in the mosquito brain. The ability of bovine insulin to stimulate a similar response further suggested this trigger is an endogenous insulin-like peptide (ILP). A. aegypti encodes eight… CONTINUE READING
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