An inpatient study of the effects of buprenorphine on cigarette smoking in men concurrently dependent on cocaine and opioids.

@article{Mutschler2002AnIS,
  title={An inpatient study of the effects of buprenorphine on cigarette smoking in men concurrently dependent on cocaine and opioids.},
  author={Nicole H. Mutschler and Bruce Stephen and Siew Koon Teoh and Jack H. Mendelson and Nancy K. Mello},
  journal={Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco},
  year={2002},
  volume={4 2},
  pages={
          223-8
        }
}
The effect of sublingual buprenorphine on cigarette smoking was examined in 23 adult men with DSM III-R diagnosis of concurrent opiate and cocaine dependence. After admission to a clinical research ward, subjects were detoxified with methadone (10-50 mg/day), then were drug-free for 6 days before random assignment to either 4 or 8 mg/day of buprenorphine. Gradually increasing daily sublingual doses of buprenorphine were administered for 5 days, then subjects were maintained on 4 or 8 mg/day of… CONTINUE READING

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