An injectable calcium phosphate cement for the local delivery of paclitaxel to bone.

@article{LopezHeredia2011AnIC,
  title={An injectable calcium phosphate cement for the local delivery of paclitaxel to bone.},
  author={Marco Antonio Lopez-Heredia and G J Bernard Kamphuis and Peter C. Th{\"u}ne and Fetullah Cumhur {\"O}ner and John A. Jansen and X Frank Walboomers},
  journal={Biomaterials},
  year={2011},
  volume={32 23},
  pages={
          5411-6
        }
}
Bone metastases are usually treated by surgical removal, fixation and chemotherapeutic treatment. Bone cement is used to fill the resection voids. The aim of this study was to develop a local drug delivery system using a calcium phosphate cement (CPC) as carrier for chemotherapeutic agents. CPC consisted of alpha-tricalcium phosphate, calcium phosphate dibasic and precipitated hydroxyapatite powders and a 2% Na(2)HPO(4) hardening solution. Scanning electron microscopy (SEM) was used to observe… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

The curability of breast cancer and the treatment of advanced disease

  • European Journal of Nuclear Medicine and Molecular Imaging
  • 2004
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

The antitumor ef fi cacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery

M Itokazu, M Esaki, K Yamamoto, T Tanemori, T Kasai
  • Biomaterials
  • 2011

The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery. Biomaterials 2011;32(12):3285e302

Yao H-J, Ju R-J, +3 authors Y Yu
  • 2011

complications from prostate cancer

A Lipton
  • 2011

metastasis : how the skeleton affects tumor behavior

SM Kakonen, GR Mundy
  • 2011

Similar Papers

Loading similar papers…