An inherited translocation t(4;15) (p16;q22) leading to two cases of partial trisomy 15.

@article{Cohen1975AnIT,
  title={An inherited translocation t(4;15) (p16;q22) leading to two cases of partial trisomy 15.},
  author={M. Michael Cohen and Asher Ornoy and Ada Rosenmann and Gertrude Kohn},
  journal={Annales de genetique},
  year={1975},
  volume={18 2},
  pages={99-103}
}
A four year old girl with severe mental retardation and multiple congenital abnormalities manifested "partial trisomy 15". Her mother, pregnant at the time of examination, possessed a balanced translocation which, after banding techniques, was identified as t(4;15)(p16;q22). Amnio-centesis revealed the karyotype of the fetus to be identical to that of the proposita and a therapeutic abortion was performed. Prenatal investigation of a subsequent pregnancy revealed a normal male karyotype… CONTINUE READING

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