An inherited efficiencies model of non-genomic evolution

@article{New2000AnIE,
  title={An inherited efficiencies model of non-genomic evolution},
  author={Michael H. New and Andrew Pohorille},
  journal={Simul. Pr. Theory},
  year={2000},
  volume={8},
  pages={99-108}
}
A model for the evolution of biological systems in the absence of a nucleic acid-like genome is proposed and applied to model the earliest living organisms -protocells composed of membrane encapsulated peptides. Assuming that the peptides can make and break bonds between amino acids, and bonds in nonfunctional peptides are more likely to be destroyed than in functional peptides, it is demonstrated that the catalytic capabilities of the system as a whole can increase. This increase is defined to… CONTINUE READING

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Szostak: "Ribozymes: Aiming at RNA replication and peptide synthesis.

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