An influx of macrophages is the predominant local immune response in ovine pulmonary adenocarcinoma.

@article{Summers2005AnIO,
  title={An influx of macrophages is the predominant local immune response in ovine pulmonary adenocarcinoma.},
  author={Christina Summers and Mary Norval and Marcelo De Las Heras and Lorenzo Gonz{\'a}lez and James Michael Sharp and Gregory J. M. Woods},
  journal={Veterinary immunology and immunopathology},
  year={2005},
  volume={106 3-4},
  pages={285-94}
}
Infection with a retrovirus, Jaagsiekte sheep retrovirus (JSRV), causes ovine pulmonary adenocarcinoma (OPA). The excess production of surfactant proteins by alveolar tumour cells results in increased production of pulmonary fluid, which is characteristically expelled through the nostrils of affected sheep. The immune response to JSRV and the tumour is poorly understood: no JSRV-specific circulating antibodies or T cells have been detected to date. The aim of the present study was to obtain… CONTINUE READING

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