An inexpensive, specific and highly sensitive protocol to detect the BrafV600E mutation in melanoma tumor biopsies and blood.

Abstract

The Braf(V600E) mutation has been detected in patients with metastatic melanoma, colon, thyroid and other cancers. Recent studies suggested that tumors with this mutation are especially sensitive to Braf inhibitors, hence the need to reliably determine the Braf status of tumor specimens. The present technologies used to screen for this mutation fail to… (More)
DOI: 10.1097/CMR.0b013e32833d8d48

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Cite this paper

@article{Panka2010AnIS, title={An inexpensive, specific and highly sensitive protocol to detect the BrafV600E mutation in melanoma tumor biopsies and blood.}, author={David J. Panka and Ryan Sullivan and James Walter Mier}, journal={Melanoma research}, year={2010}, volume={20 5}, pages={401-7} }