An increased calcium sensitivity of mesenteric resistance vessels in young and adult spontaneously hypertensive rats.

@article{Mulvany1980AnIC,
  title={An increased calcium sensitivity of mesenteric resistance vessels in young and adult spontaneously hypertensive rats.},
  author={Michael J. Mulvany and Niels C Berg Nyborg},
  journal={British journal of pharmacology},
  year={1980},
  volume={71 2},
  pages={585-96}
}
1. We have measured the calcium sensitivity in response to noradrenaline stimulation and potassium depolarization of isolated segments of 100 to 200 micrometer mesenteric resistance vessels from spontaneously hypertensive (SHR) and control Wistar-Kyoto rats. The rats were either young (4 wk) or adult (4 months), that is of ages before or after the SHRs had developed elevated blood pressure. Experiments were performed under conditions in which the effect of noradrenaline uptake by, and the… CONTINUE READING