An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle.

@article{Drummond2010AnII,
  title={An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle.},
  author={Micah J Drummond and Erin L. Glynn and Christopher S Fry and Kyle L. Timmerman and Elena Volpi and Blake B Rasmussen},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2010},
  volume={298 5},
  pages={E1011-8}
}
Essential amino acids (EAA) stimulate skeletal muscle mammalian target of rapamycin complex 1 (mTORC1) signaling and protein synthesis. It has recently been reported that an increase in amino acid (AA) transporter expression during anabolic conditions is rapamycin-sensitive. The purpose of this study was to determine whether an increase in EAA availability increases AA transporter expression in human skeletal muscle. Muscle biopsies were obtained from the vastus lateralis of seven young adult… CONTINUE READING
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