An inactivated, oil-emulsion vaccine for the prevention of porcine parvovirus-induced reproductive failure.

@article{Wrathall1984AnIO,
  title={An inactivated, oil-emulsion vaccine for the prevention of porcine parvovirus-induced reproductive failure.},
  author={Anthony E Wrathall and David E Wells and SHEILA. F. CARTWRIGHT and G. N. Frerichs},
  journal={Research in veterinary science},
  year={1984},
  volume={36 2},
  pages={136-43}
}
Pig fetuses inoculated at 45 days gestation with virulent porcine parvovirus (PPV) were harvested 10 days later. Virus was extracted, inactivated with binary ethylenimine and the antigen suspension emulsified with mineral oil adjuvant. One dose of this vaccine, or two doses with a 14 day interval, stimulated high and long lasting serum antibody titres in gilts. Vaccination caused no clinical reactions and lesions at injection sites were minor. Vaccination of seronegative gilts at 40 days… CONTINUE READING

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