An in vivo study on adjudin and blood-testis barrier dynamics.

@article{Kopera2009AnIV,
  title={An in vivo study on adjudin and blood-testis barrier dynamics.},
  author={Ilona A Kopera and Linlin Su and Barbara Bilińska and Chung-ying Cheng and Dolores Dorothy Mruk},
  journal={Endocrinology},
  year={2009},
  volume={150 10},
  pages={
          4724-33
        }
}
Adjudin is known to specifically affect Sertoli-germ cell adhesion, resulting in germ cell loss from the seminiferous epithelium and transient infertility. The apical ectoplasmic specialization (ES) was shown to be the primary target of adjudin because adhesion was unaffected in organs that lack this structure. Herein we expand previous findings by treating rat pups with adjudin, and we aimed to address two questions. First, can adjudin perturb germ cell adhesion in the seminiferous epithelium… CONTINUE READING
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