An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO₂ inhalation exposures.

@article{Demokritou2013AnIV,
  title={An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO₂ inhalation exposures.},
  author={Philip Demokritou and Samuel Gass and Georgios Pyrgiotakis and Joel M. Cohen and William M. Goldsmith and Walt McKinney and David Frazer and Jane Ma and Diane E Schwegler-Berry and Joseph Brain and Vincent Castranova},
  journal={Nanotoxicology},
  year={2013},
  volume={7 8},
  pages={1338-50}
}
Nanoscale CeO₂ is increasingly used for industrial and commercial applications, including catalysis, UV-shielding and as an additive in various nanocomposites. Because of its increasing potential for consumer and occupational exposures, a comprehensive toxicological characterisation of this nanomaterial is needed. Preliminary results from intratracheal instillation studies in rats point to cytotoxicity and inflammation, though these studies may not accurately use realistic nanoscale exposure… CONTINUE READING
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