An in vitro system to study tumor dormancy and the switch to metastatic growth.

@article{Barkan2011AnIV,
  title={An in vitro system to study tumor dormancy and the switch to metastatic growth.},
  author={Dalit Barkan and Jeffrey E. Green},
  journal={Journal of visualized experiments : JoVE},
  year={2011},
  volume={54}
}
Recurrence of breast cancer often follows a long latent period in which there are no signs of cancer, and metastases may not become clinically apparent until many years after removal of the primary tumor and adjuvant therapy. A likely explanation of this phenomenon is that tumor cells have seeded metastatic sites, are resistant to conventional therapies… CONTINUE READING