An in vitro study of mucoadhesion and biocompatibility of polymer coated liposomes on HT29-MTX mucus-producing cells.

@article{Adamczak2016AnIV,
  title={An in vitro study of mucoadhesion and biocompatibility of polymer coated liposomes on HT29-MTX mucus-producing cells.},
  author={Małgorzata Adamczak and Ellen Hagesaether and Gro Smistad and Marianne Hiorth},
  journal={International journal of pharmaceutics},
  year={2016},
  volume={498 1-2},
  pages={
          225-33
        }
}
Drug delivery to the oral cavity poses a significant challenge due to the short residence time of the formulations at the site of action. From this point of view, nanoparticulate drug delivery systems with ability to adhere to the oral mucosa are advantageous as they could increase the effectiveness of the therapy. Positively, negatively and neutrally charged liposomes were coated with four different types of polymers: alginate, low-ester pectin, chitosan and hydrophobically modified ethyl… CONTINUE READING

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Formulation of polysaccharide‐based nanoparticles for local administration into the oral cavity

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