An in vitro model to assess mechanisms and efficacy of a cellular conduit for treatment of avascular meniscal injuries

@article{Fox2008AnIV,
  title={An in vitro model to assess mechanisms and efficacy of a cellular conduit for treatment of avascular meniscal injuries},
  author={D. Fox and Jill K. Luther and D. Whitener},
  journal={In Vitro Cellular & Developmental Biology - Animal},
  year={2008},
  volume={44},
  pages={185-188}
}
Tears in the avascular portion of the knee meniscus are commonplace and are frequently incapable of healing spontaneously. Delivery of synovial cells from the meniscal periphery to avascular injuries can result in an effective healing response but is difficult to accomplish surgically. This report describes the development of a novel in vitro model comprised of three-dimensionally cultured cells in agarose used to assess the proof of concept that a cellular conduit device could be used to… Expand
3 Citations
Cell-based Meniscal Tissue Engineering: A Case for Synoviocytes
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Effect of media mixing on ECM assembly and mechanical properties of anatomically-shaped tissue engineered meniscus.
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