An in vitro model of mycobacterial granuloma to investigate the immune response in brain-injured patients.


OBJECTIVE We investigated the overall immune response to pathogens in brain-injured patients, and assessed its relationship to nosocomial pneumonia. DESIGN Observational study. SETTING Two surgical ICUs of a single institution. PATIENTS Severe brain-injured patients (n = 32) requiring mechanical ventilation and sex- and age-matched healthy donors (n… (More)
DOI: 10.1097/CCM.0b013e3182676052


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