An in vitro model of ischemic stroke.

  title={An in vitro model of ischemic stroke.},
  author={Li Yang and Kaushik K Shah and Thomas J Abbruscato},
  journal={Methods in molecular biology},
Brain stroke is a devastating cerebrovascular disease and ranks as the third most common cause of death and disability in the US. Altered blood-brain barrier (BBB) signaling and permeability characteristics during stroke can increase the risk for life-threatening hemorrhagic transformation or damaging brain edema. The BBB plays a crucial role in maintaining the permeability and CNS homeostasis under physiological/pathological conditions by protecting the brain from the fluctuations in plasma… CONTINUE READING

Similar Papers

Loading similar papers…