An in vitro model of ischemic stroke.

@article{Yang2012AnIV,
  title={An in vitro model of ischemic stroke.},
  author={Li Yang and Kaushik K Shah and Thomas J Abbruscato},
  journal={Methods in molecular biology},
  year={2012},
  volume={814},
  pages={
          451-66
        }
}
Brain stroke is a devastating cerebrovascular disease and ranks as the third most common cause of death and disability in the US. Altered blood-brain barrier (BBB) signaling and permeability characteristics during stroke can increase the risk for life-threatening hemorrhagic transformation or damaging brain edema. The BBB plays a crucial role in maintaining the permeability and CNS homeostasis under physiological/pathological conditions by protecting the brain from the fluctuations in plasma… CONTINUE READING
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