An in vitro model of human red blood cell production from hematopoietic progenitor cells.

Abstract

Hemoglobinopathies, such as beta-thalassemias and sickle cell anemia (SCA), are among the most common inherited gene defects. Novel models of human erythropoiesis that result in terminally differentiated red blood cells (RBCs) would be able to address the pathophysiological abnormalities in erythrocytes in congenital RBC disorders and to test the potential… (More)

Topics

5 Figures and Tables

Slides referencing similar topics