An in vitro micromethod for drug sensitivity testing of Leishmania.

Abstract

We describe an in vitro microtest which is quantitative, rapid, and readily applicable to parasites isolated from all major forms of human leishmaniasis. It is based on drug-mediated inhibition of promastigote catabolism of a battery of simple 14C-substrates to 14CO2. Each test requires less than 1 microCi. The test is conducted in a serum-free, chemically… (More)

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Cite this paper

@article{Jackson1989AnIV, title={An in vitro micromethod for drug sensitivity testing of Leishmania.}, author={Joan E. Jackson and Jacob Tally and Douglas B. Tang}, journal={The American journal of tropical medicine and hygiene}, year={1989}, volume={41 3}, pages={318-30} }