An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons.

Abstract

The currently accepted scheme for reactive oxygen species production during ischemia/reperfusion injury is characterized by a deleterious mitochondria-derived burst of radical generation during reperfusion; however, recent examination of the penumbra suggests a central role for NADPH-oxidase (Nox)-mediated radical generation during the ischemic period… (More)
DOI: 10.1016/j.brainres.2012.03.004

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Cite this paper

@article{Pamenter2012AnIV, title={An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons.}, author={Matthew Edward Pamenter and Sameh S Ali and Qingbo Tang and Jennifer C. Finley and Xiang Gu and Laura Dugan and Gabriel G. Haddad}, journal={Brain research}, year={2012}, volume={1452}, pages={165-72} }