An in vitro investigation into the potential for bimodal drug release from pectin/chitosan/HPMC-coated tablets.

The influence of disintegrant on the water uptake and subsequent disintegration force developed was investigated in a simple tablet formulation. The results indicated that a reasonable correlation existed between water uptake and disintegration force for the disintegrants screened with cross linked polyvinyl pyrrolidone (PVP XL) showing a proportionally… CONTINUE READING