An in vitro analysis of central venous drug delivery by continuous infusion: the effect of manifold design and port selection.

@article{Moss2009AnIV,
  title={An in vitro analysis of central venous drug delivery by continuous infusion: the effect of manifold design and port selection.},
  author={David R. Moss and Karsten Bartels and Gregory L. Peterfreund and Mark A Lovich and Nathaniel M. Sims and Robert A. Peterfreund},
  journal={Anesthesia and analgesia},
  year={2009},
  volume={109 5},
  pages={1524-9}
}
BACKGROUND Central venous catheters are used extensively in anesthesia and critical care. Multiport manifolds allow for simultaneous administration of multiple medication infusions into a common central venous catheter lumen. The structures of such manifolds vary considerably. In this study, we quantitatively compared, in a laboratory model of continuous drug infusion, the drug delivery dynamics of a traditional stopcock manifold and a microinfusion manifold constructed to minimize dead volume… CONTINUE READING
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