An in situ-hybridization study of the localization of retinol-binding protein and transthyretin messenger RNAs during fetal development in the rat.

@article{Makover1989AnIS,
  title={An in situ-hybridization study of the localization of retinol-binding protein and transthyretin messenger RNAs during fetal development in the rat.},
  author={A Makover and Dianne Robert Soprano and Marcie Wyatt and Dewitt S. Goodman},
  journal={Differentiation; research in biological diversity},
  year={1989},
  volume={40 1},
  pages={17-25}
}
The patterns, and the cellular sites, of expression of the genes for retinol-binding protein (RBP) and transthyretin (TTR) were studied during early- to mid-stages of rat embryogenesis. In situ hybridization of single-stranded RNA probes to rat embryo sections revealed specific sites at which RBP messenger RNA (mRNA) and TTR mRNA were localized in rat conceptuses from 7 to 13 days of gestation. RBP and TTR mRNAs were both observed in the visceral endoderm as early as at 7 days of gestation. The… CONTINUE READING