An in situ gelling buccal spray containing platelet lysate for the treatment of oral mucositis.

@article{Sandri2011AnIS,
  title={An in situ gelling buccal spray containing platelet lysate for the treatment of oral mucositis.},
  author={Giuseppina Sandri and Maria Cristina Bonferoni and Franca Ferrari and Silvia Rossi and Claudia Del Fante and C Cabrejos Perotti and Angelo Gallanti and Carla Marcella Caramella},
  journal={Current drug discovery technologies},
  year={2011},
  volume={8 3},
  pages={
          277-85
        }
}
Oral mucositis is an inflammatory disease of the mucosa lining oral cavity which leads to atrophy of the epithelium and to its ulceration to form chronic lesions. Many studies, both in vitro and in vivo, have disclosed the effectiveness of growth factors derived from platelets to enhance cell proliferation, differentiation, chemotaxis, angiogenesis and extracellular matrix synthesis involved in the healing of tissues. Despite potential usefulness of growth factors, animal-derived or genetically… CONTINUE READING
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