An in-situ forming skin substitute improves healing outcome in a hypertrophic scar model.

@article{Hartwell2015AnIF,
  title={An in-situ forming skin substitute improves healing outcome in a hypertrophic scar model.},
  author={Ryan V Hartwell and Malihe-Sadat Poormasjedi-Meibod and Claudia Ch{\'a}vez-Mu{\~n}oz and Reza Jalili and Azadeh Hossenini-Tabatabaei and Aziz Ghahary},
  journal={Tissue engineering. Part A},
  year={2015},
  volume={21 5-6},
  pages={1085-94}
}
Wound repair requires a sequential series of biological events that begins with the deposition of a temporary scaffold within which cells can repair the skin. Without a scaffold, repair is essentially impossible. Aberrant wound healing, such as hypertrophic scarring or nonhealing, has a tremendous burden on healthcare and quality of life. Timely wound closure dramatically reduces the risk of infection and scarring. Cellular skin substitutes are opportune to meet this need. Our goal was to… CONTINUE READING