An improved technique for repeated bronchoalveolar lavage and lung mechanics measurements in individual rats.

@article{Novk2006AnIT,
  title={An improved technique for repeated bronchoalveolar lavage and lung mechanics measurements in individual rats.},
  author={Zolt{\'a}n Nov{\'a}k and Ferenc Pet{\'a}k and Andrea B{\'a}nfi and Val{\'e}ria T{\'o}th-Szűki and Levente Bar{\'a}ti and Lajos K{\'o}sa and Ferenc Bari and Edg{\'a}r A Sz{\'e}kely},
  journal={Respiratory physiology & neurobiology},
  year={2006},
  volume={154 3},
  pages={467-77}
}
Lung function and bronchoalveolar lavage (BAL) fluid are commonly analyzed to assess the severity of lung disease in sacrificed animals. The input impedance of the respiratory system (Z(rs)) was measured and BAL fluid was collected in intubated, anesthetized, mechanically ventilated rats on three occasions 1 week apart. Measurements were performed in control animals (group C), while lung injury was induced in the other group (group LPS) by i.p. injection of lipopolysaccharide (LPS) before the… CONTINUE READING