An improved procedure for the synthesis of glycine and taurine conjugates of bile acids.

@article{Tserng1977AnIP,
  title={An improved procedure for the synthesis of glycine and taurine conjugates of bile acids.},
  author={K Y Tserng and David L. Hachey and Peter D. Klein},
  journal={Journal of lipid research},
  year={1977},
  volume={18 3},
  pages={404-7}
}
Glycine and taurine conjugates of 5beta-cholanic acids have been synthesized using improved procedures based on the peptide coupling reagent, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. The conjugates are obtained in chromatographically pure form in yields higher than 90%. The use of this procedure in the large scale preparation of cholyl[1,2-13C2]glycine is described. 

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Preparation of conjugated bile acids using mixed carboxylic acid anhydrides . Bile acids and steroids

A. F. Hofmann
Ark . Kemi . • 1955

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