An improved micromethod for theophylline determination by reversed-phase liquid chromatography.

Abstract

We describe an improved micro-scale method for determining serum theophylline by reversed-phase liquid chromatography. Samples are deproteinized with two volumes of methanol containing beta-hydroxyethyltheophylline as an internal standard. The supernate is chromatographed with a methanol/sodium acetate buffer (15/85 by vol) mobile phase, and the amount of… (More)

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Cite this paper

@article{Butrimovitz1979AnIM, title={An improved micromethod for theophylline determination by reversed-phase liquid chromatography.}, author={G P Butrimovitz and Vidmantas A Raisys}, journal={Clinical chemistry}, year={1979}, volume={25 8}, pages={1461-4} }