An improved LC-MS/MS method for quantitation of indapamide in whole blood: application for a bioequivalence study.

Abstract

An improved LC-MS/MS method for the quantitation of indapamide in human whole blood was developed and validated. Indapamide-d3 was used as internal standard (IS) and liquid-liquid extraction was employed for sample preparation. LC separation was performed on Synergi Polar RP-column (50 × 4.6 mm i.d.; 4 µm) and mobile phase composed of methanol and 5 mm… (More)
DOI: 10.1002/bmc.3148

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