An important role for protein kinase C-delta in human keratinocyte migration on dermal collagen.

@article{Li2002AnIR,
  title={An important role for protein kinase C-delta in human keratinocyte migration on dermal collagen.},
  author={Wei W. Li and Celina M Nadelman and Noah S Gratch and Weiquin Li and Mei Chen and Nori Kasahara and David T. Woodley},
  journal={Experimental cell research},
  year={2002},
  volume={273 2},
  pages={219-28}
}
Migration of human keratinocytes plays a critical role in the re-epithelialization of human skin wounds, the process by which the wound bed is resurfaced and closed by keratinocytes as it forms a new epidermis. While the importance of ECM components and serum factors in the regulation of keratinocytes motility is well established, the intracellular signaling mechanisms remain fragmentary. In this study, we investigated the role of protein kinase Cdelta (PKCdelta) signaling in the promotion of… CONTINUE READING