An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice

@inproceedings{Akbar2015AnIR,
  title={An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice},
  author={Naveed Akbar and Sambit Kumar Nanda and Jill J. F. Belch and Philip Cohen and Faisel Khan},
  booktitle={Arthritis research & therapy},
  year={2015}
}
INTRODUCTION The link between cardiovascular disease (CVD) and patients with chronic inflammation is not clearly understood. We examined a knock-in mouse expressing a poly-ubiquitin-binding-defective mutant of the protein ABIN1 (ABIN1(D485N)), which develops a systemic lupus erythematosus-like autoimmune disease because of the hyperactivation of IκB kinases… CONTINUE READING