An immunological basis for inhibition of transformation of human lymphocytes by EB virus

Abstract

IT is well known that Epstein–Barr virus (EBV) transforms human lymphocytes in vitro, and lymphoblastoid cell lines are established1. Macrophages enhance transformation by EBV in vitro2 but may not be essential3. Inhibition of transformation by EBV in vitro has also been reported, and was first observed when lymphocytes from an adult donor with antibody to… (More)
DOI: 10.1038/268735a0

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