An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies

@article{Silva2006AnIS,
  title={An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies},
  author={Rohan de Silva and Tammaryn Lashley and Catherine Strand and Anna-Maria Shiarli and Jing Shi and Jinzhou Tian and Kathryn L. Bailey and Peter Davies and Eileen H. Bigio and Kunimasa Arima and Eizo Iseki and Shigeo Murayama and Hans A. Kretzschmar and Manuela Neumann and Carol Lippa and Glenda Halliday and James W. Mackenzie and Rivka Ravid and Dennis Dickson and Zbigniew Wszolek and Takeshi Iwatsubo and Stuart M. Pickering-Brown and Janice Holton and A. J. Lees and Tam{\'a}s R{\'e}v{\'e}sz and David M. A. Mann},
  journal={Acta Neuropathologica},
  year={2006},
  volume={111},
  pages={329-340}
}
The pathological distinctions between the various clinical and pathological manifestations of frontotemporal lobar degeneration (FTLD) remain unclear. Using monoclonal antibodies specific for 3- and 4-repeat isoforms of the microtubule associated protein, tau (3R- and 4R-tau), we have performed an immunohistochemical study of the tau pathology present in 14 cases of sporadic forms of FTLD, 12 cases with Pick bodies and two cases without and in 27 cases of familial FTLD associated with 12… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 65 REFERENCES

High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands

P Rizzu, JC van Swieten, +10 authors P Heutink
  • Am J Hum Genet
  • 1999
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

The evolution and pathology of frontotemporal dementia

A Kertesz, P McGonagle, M Blair, W Davidson, DG Munoz
  • Brain
  • 2005
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy

Marion Hogg, Zoran M. Grujic, +21 authors Eileen H. Bigio
  • Acta Neuropathologica
  • 2003
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL