An immunohistochemical study of TIMP-3 expression in oesophageal squamous cell carcinoma

@article{Miyazaki2004AnIS,
  title={An immunohistochemical study of TIMP-3 expression in oesophageal squamous cell carcinoma},
  author={Tatsuya Miyazaki and H. Ogata H. Kato and Masanobu Nakajima and Ahmad Faried and Junko Takita and Makoto Sohda and Yasuyuki Fukai and Satoru Yamaguchi and Norihiro Masuda and Ryokuhei Manda and Minoru Fukuchi and Hitoshi Ojima and Katsuhiko Tsukada and Hiroyuki Kuwano},
  journal={British Journal of Cancer},
  year={2004},
  volume={91},
  pages={1556 - 1560}
}
Tissue inhibitor of metalloproteinase-3 (TIMP-3) inhibits the activity of matrix metalloproteinase, which may play an important role in carcinoma invasion and metastasis. We have investigated the relationship between TIMP-3 reduction and clinicopathological factors in oesophageal squamous cell carcinoma (ESCC). We examined tissue specimens that had been removed from 90 patients with thoracic oesophageal cancer who had undergone surgery between 1983 and 2001. Immunohistochemical staining was… CONTINUE READING

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