An immunoblot study of neurofilament degradation in situ and during calcium-activated proteolysis.

@article{Schlaepfer1985AnIS,
  title={An immunoblot study of neurofilament degradation in situ and during calcium-activated proteolysis.},
  author={W. W. Schlaepfer and Chaekyun Lee and V M.-Y. Lee and U J Zimmerman},
  journal={Journal of neurochemistry},
  year={1985},
  volume={44 2},
  pages={502-9}
}
The degradation of neurofilament (NF) proteins was examined by immunoblot methods to identify, characterize, and monitor the appearance of immunoreactive breakdown products during the loss of NF triplet proteins. Individual NF proteins and their breakdown products were identified using polyclonal and monoclonal antibodies to NF proteins. NF degradation was compared during calcium-activated proteolysis of isolated rat NF, during an experimental influx of calcium into excised rat spinal nerve… CONTINUE READING

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