An immune pathological and ultrastructural skin analysis for rhododenol-induced leukoderma patients.

@article{Tanemura2015AnIP,
  title={An immune pathological and ultrastructural skin analysis for rhododenol-induced leukoderma patients.},
  author={Atsushi Tanemura and Lingli Yang and Fei Yang and Yuiko Nagata and Mari Wataya-Kaneda and Kazuyoshi Fukai and Daisuke Tsuruta and Rintaro Ohe and Mitsunori Yamakawa and Tamio Suzuki and Ichiro Katayama},
  journal={Journal of dermatological science},
  year={2015},
  volume={77 3},
  pages={
          185-8
        }
}
As reported in the mass media on July 2013, numerous consumers who had used the cosmetic ingredient containing rhododendrol (4-(4-hydroxyphenyl)-2-butanol, Trade name; rhododenol), which is a melanin inhibitor isolated from Acer nikoense Maxim, released from Kanebo Cosmetics Inc. (Tokyo, Japan) noticed leukoderma patches on their face, neck and hands. We have experienced 32 cases that developed leukoderma after using such cosmetics so far and skin biopsy samples in some cases were obtained from… CONTINUE READING

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