An image processing algorithm for accurate extraction of the centerline from human metaphase chromosomes

@article{Arachchige2010AnIP,
  title={An image processing algorithm for accurate extraction of the centerline from human metaphase chromosomes},
  author={Akila Subasinghe Arachchige and Jagath Samarabandu and Joan Knoll and Wahab Khan and Peter K. Rogan},
  journal={2010 IEEE International Conference on Image Processing},
  year={2010},
  pages={3613-3616}
}
The study of human metaphase chromosomes is an important aspect in clinical diagnosis of genetic disorders. Although many image processing techniques have been developed for chromosomal karyotyping to assist in laboratory diagnosis, they fail to provide reliable results in segmenting and extracting the centerline of chromosomes due to their shape variability when placed on microscope slides. In this paper we propose a hybrid algorithm that uses Gradient Vector Flow active contours, Discrete… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 12 REFERENCES

Thinning Methodologies - A Comprehensive Survey

  • IEEE Trans. Pattern Anal. Mach. Intell.
  • 1992
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Skeleton Pruning by Contour Partitioning with Discrete Curve Evolution

  • IEEE Transactions on Pattern Analysis and Machine Intelligence
  • 2007
VIEW 2 EXCERPTS

Gradient vector flow: a new external force for snakes

  • Proceedings of IEEE Computer Society Conference on Computer Vision and Pattern Recognition
  • 1997
VIEW 2 EXCERPTS