An fMRI-based neurologic signature of physical pain.

  title={An fMRI-based neurologic signature of physical pain.},
  author={Tor D. Wager and Lauren Y. Atlas and Martin A. Lindquist and Mathieu Roy and Choong-Wan Woo and Ethan Kross},
  journal={The New England journal of medicine},
  volume={368 15},
BACKGROUND Persistent pain is measured by means of self-report, the sole reliance on which hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds promise for identifying objective measures of pain, but brain measures that are sensitive and specific to physical pain have not yet been identified. METHODS In four studies involving a total of 114 participants, we developed an fMRI-based measure that predicts pain intensity at the level of the individual person. In… CONTINUE READING
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