An extended Tajima's D neutrality test incorporating SNP calling and imputation uncertainties.

Abstract

To identify evolutionary events from the footprints left in the patterns of genetic variation in a population, people use many statistical frameworks, including neutrality tests. In datasets from current high throughput sequencing and genotyping platforms, it is common to have missing data and low-confidence SNP calls at many segregating sites. However, the… (More)

Topics

  • Presentations referencing similar topics