An exploratory study of articular cartilage and subchondral bone reconstruction with bone marrow mesenchymal stem cells combined with porous tantalum/Bio-Gide collagen membrane in osteonecrosis of the femoral head.

@article{Liu2019AnES,
  title={An exploratory study of articular cartilage and subchondral bone reconstruction with bone marrow mesenchymal stem cells combined with porous tantalum/Bio-Gide collagen membrane in osteonecrosis of the femoral head.},
  author={Baoyi Liu and Fan Yang and Xiaowei Wei and Xiuzhi Zhang and Yu Zhang and Benjie Wang and Ge Liu and Hui Hui Xie and Jiahui Yang and Wei Wang and Kairong Qin and Dewei Zhao},
  journal={Materials science & engineering. C, Materials for biological applications},
  year={2019},
  volume={99},
  pages={
          1123-1132
        }
}
Osteonecrosis of the femoral head (ONFH) results in collapse of the femoral head and rapid destruction of the hip joint. The repair of post-collapse articular cartilage and subchondral bone is challenging. We interrupted the blood supply to the femoral head and established a full-thickness articular defect animal model after ONFH was determined via X-ray. Porous tantalum and a Bio-Gide collagen membrane, co-cultured with bone marrow mesenchymal stem cells (BMSCs) in vitro, were implanted into… CONTINUE READING
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