An explanation for gallstones in normal-weight women: slow intestinal transit.

@article{Heaton1993AnEF,
  title={An explanation for gallstones in normal-weight women: slow intestinal transit.},
  author={Kenneth W. Heaton and Pauline M Emmett and Carol Symes and F. E. M. Braddon},
  journal={Lancet},
  year={1993},
  volume={341 8836},
  pages={8-10}
}
Many cases of gallstones can be explained in terms of the established risk factors, especially obesity. However, gallstones develop in some women who are not obese, and the causes are unknown. Biochemical studies have shown that slow intestinal transit is associated with lithogenic bile. We have tested the hypothesis that intestinal transit is abnormally slow in normal-weight women with gallstones. In a population survey, 1058 women aged 25-69 years, registered with general practitioners in… CONTINUE READING

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