An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92

@inproceedings{Charusanti2011AnEG,
  title={An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92},
  author={Pep Charusanti and Sadhana Chauhan and Kathleen McAteer and Joshua A. Lerman and Daniel R. Hyduke and Vladimir L. Motin and Charles Ansong and Joshua N. Adkins and Bernhard O. Palsson},
  booktitle={BMC Systems Biology},
  year={2011}
}
Yersinia pestis is a gram-negative bacterium that causes plague, a disease linked historically to the Black Death in Europe during the Middle Ages and to several outbreaks during the modern era. Metabolism in Y. pestis displays remarkable flexibility and robustness, allowing the bacterium to proliferate in both warm-blooded mammalian hosts and cold-blooded insect vectors such as fleas. Here we report a genome-scale reconstruction and mathematical model of metabolism for Y. pestis CO92 and… CONTINUE READING
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