An experimental study of acute radiation-induced cognitive dysfunction in a young rat model.

@article{Liu2010AnES,
  title={An experimental study of acute radiation-induced cognitive dysfunction in a young rat model.},
  author={Yi-zhi Liu and Shang-wen Xiao and Jun-feng Liu and Huaisheng Zhou and Zhiheng Liu and Yanzhong Xin and William Z. Suo},
  journal={AJNR. American journal of neuroradiology},
  year={2010},
  volume={31 2},
  pages={383-7}
}
BACKGROUND AND PURPOSE Radiation-induced cognitive dysfunction is a common and serious clinical complication after radiation therapy for a brain tumor, but the knowledge of its mechanism is poorly understood. The purpose of this study was to establish a young rat model for acute radiation-induced cognitive dysfunction and associated BBB damage, as well as histopathologic changes. MATERIALS AND METHODS Young male rats were randomized into 4 groups to receive irradiation treatments at 300 cGy… CONTINUE READING

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