An experimental model for the study of well differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors

@inproceedings{Peng2011AnEM,
  title={An experimental model for the study of well differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors},
  author={Tingsheng Peng and Pingyu Zhang and J. Rebecca Liu and Theresa P Nguyen and Svetlana Bolshakov and Roman Belousov and Eric D. Young and Xiaoke Wang and Kari J Brewer and Lola Lopez Terrada and Andr{\'e} Luiz Malavasi Longo de Oliveira and Alexander J Lazar and Dina Chelouche Lev},
  booktitle={Laboratory Investigation},
  year={2011}
}
Therapeutic progress in well-differentiated/dedifferentiated liposarcoma (WDLPS/DDLPS) is hampered by lack of relevant experimental models, thereby limiting comprehensive molecularly based investigations. Our goal is to bridge this experimental gap by establishing and characterizing an in vitro/in vivo model useful for examining WDLPS/DDLPS molecular pathogenesis and also therapeutic screening and testing. WDLPS/DDLPS cells were isolated from freshly resected human surgical specimens and were… CONTINUE READING