An expanded family of arrestins regulate metabolism.

  title={An expanded family of arrestins regulate metabolism.},
  author={Parth Patwari and Richard T Lee},
  journal={Trends in endocrinology and metabolism: TEM},
  volume={23 5},
The classical visual and β-arrestins belong to a larger family of proteins that likely share structural similarity. Humans have an additional six related proteins sometimes termed the α-arrestins, whose functions are now emerging. Surprisingly, several α-arrestins play prominent roles in the regulation of metabolism and obesity. One α-arrestin, thioredoxin-interacting protein (Txnip), has crucial functions in regulating glucose uptake and glycolytic flux through the mitochondria. Another… CONTINUE READING

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