An exo-alpha-sialidase from bifidobacteria involved in the degradation of sialyloligosaccharides in human milk and intestinal glycoconjugates.

@article{Kiyohara2011AnEF,
  title={An exo-alpha-sialidase from bifidobacteria involved in the degradation of sialyloligosaccharides in human milk and intestinal glycoconjugates.},
  author={Masashi Kiyohara and Kana Tanigawa and Thida Chaiwangsri and Takane Katayama and Hisashi Ashida and Kenji Yamamoto},
  journal={Glycobiology},
  year={2011},
  volume={21 4},
  pages={437-47}
}
Bifidobacteria are health-promoting enteric commensals that are assumed to proliferate predominantly in the intestines of breast-fed infants by assimilating human milk oligosaccharides (HMOs) that are frequently fucosylated and/or sialylated. We previously identified two different α-l-fucosidases in Bifidobacterium bifidum and showed that the strain furnishes an extracellular degradation pathway for fucosylated HMOs. However, the catabolism of sialylated HMOs by bifidobacteria has remained… CONTINUE READING

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