An examination of the antibacterial, antifungal, anti-Giardial and anticancer properties of Kigelia africana fruit extracts

@article{Arkhipov2014AnEO,
  title={An examination of the antibacterial, antifungal, anti-Giardial and anticancer properties of Kigelia africana fruit extracts},
  author={Alexander Arkhipov and Joseph Sirdaarta and Paran Rayan and Pauline Ann McDonnell and Ian Edwin Cock},
  journal={Pharmacognosy Communications},
  year={2014},
  volume={4},
  pages={62-76}
}
Background: Kigelia africana is a common component of the pharmacopeia's of multiple African groupings which inhabit the areas in which it grows. Amongst these groups there is a myriad of medicinal uses in the treatment of a wide variety of bacterial, fungal and protozoal infections, as well as in the treatment of cancers. This study was undertaken to test K. africana fruit extracts for the ability to inhibit microbial and cancer cell growth, and thus to validate traditional African medicinal… 

Figures and Tables from this paper

An Evaluation of the Antibacterial, Anti-Giardial, Anticancer and Toxicity Properties of Selected Nut Extracts
TLDR
The bacterial growth inhibitory activities of the methanolic almond and walnut extracts, the anti-Giardial activity of the meethanolic almonds extract and their lack of toxicity indicates the potential of these extracts in the discovery and development of new natural antibiotic agents.
An examination of the antimicrobial and anticancer properties of Garcinia cambogia fruit pericarp extracts
TLDR
The inhibitory bioactivity against a range of microbes, the anti-proliferative activity against CaCo2 and HeLa cells, as well as the lack of toxicity, indicate the potential for G. cambogia in the discovery and development of new natural pharmaceuticals.
Metabolomic Profiling of Kigelia africana Extracts with Anti-Cancer Activity by High Resolution Tandem Mass Spectroscopy
TLDR
This study was undertaken to further examine K. africana fruit extracts for the ability to inhibit cancer cell growth, and to use an unbiased metabolomic profiling approach to detect and putatively identify as many individual components as possible, with the aim of developing a database of identified compounds.
An Interactive Antimicrobial Activity of Embelica officinalis Gaertn. Fruit Extracts and Conventional Antibiotics against Some Bacterial Triggers of Autoimmune Inflammatory Diseases
TLDR
The E. officinalis fruit extracts were moderate inhibitors of the bacterial triggers of selected autoimmune inflammatory diseases, and potentiated the activity of chloramphenicol and tetracycline against otherwise resistant bacterial strains.
An Examination of the Antioxidant Capacity, Antibacterial Activity and Toxicity of Commercial Kale and Spirulina Powders
TLDR
It is indicated that aqueous kale and spirulina extracts are promising inhibitors of P. mirabilis growth and may be useful in the prevention and treatment of rheumatoid arthritis, as well as other diseases caused by that bacterium.
The Therapeutic Properties of Juniperus Communis L.: Antioxidant Capacity, Bacterial growth Inhibition, Anticancer Activity and Toxicity
TLDR
The lack of toxicity of the J. communis berry extracts and their potent growth inhibitory bioactivity against bacteria and HeLa and CaCo2 carcinoma cells indicates their potential in the treatment and prevention of selected autoimmune inflammatory diseases and some cancers.
Tabebuia impetiginosa (Mart. Ex DC. Mattos) Bark Extracts Inhibit the Growth Gastrointestinal Bacterial Pathogens and Potentiate the Activity of some Conventional Antibiotics
TLDR
T. impetiginosa bark extracts have potential in the treatment of diarrhoea and other gastrointestinal diseases and should be avoided against that bacterium.
Terminalia chebula Retz. Fruit Extracts Inhibit Bacterial Triggers of Some Autoimmune Diseases and Potentiate the Activity of Tetracycline
TLDR
T. chebula fruit methanolic, aqueous and ethyl acetate extracts displayed strong antimicrobial activity against the bacterial triggers of all autoimmune inflammatory diseases except K. pneumoniae, for which only moderate inhibition was observed.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 56 REFERENCES
An Examination of the Medicinal Potential of Pittosporum phylliraeoides: Toxicity, Antibacterial and Antifungal Activities
TLDR
The low toxicity of the P. phylliraeoides extracts and their inhibitory bioactivity against bacteria and fungi validate Australian Aboriginal usage of P.phyllirAEoides and indicates its medicinal potential.
Antifungal and antibacterial activities of the ethanolic and aqueous extract of Kigelia africana (Bignoniaceae) stem bark
TLDR
The results revealed that the crude ethanolic extract exhibited antibacterial and antifungal activities against Staphylococccus aureus and Candida albicans with zones of inhibition measuring 15.0±0.95 and 20.75±4.6mm respectively.
An examination of the medicinal potential of Scaevola spinescens: Toxicity, antibacterial, and antiviral activities
TLDR
The lack of toxicity of the S. spinescens extracts and their inhibitory bioactivity against bacteria and viruses validate the Australian Aboriginal usage of S. Spinescens and indicates its medicinal potential.
GC-MS analysis of bioactive Petalostigma extracts: Toxicity, antibacterial and antiviral activities.
TLDR
The lack of toxicity of the P. pubescens, and P. triloculare solvent extracts and their inhibitory bioactivity against bacteria and viruses validate Australian Aboriginal usage of Petalostigma species and indicates its medicinal potential.
Evaluation of the potential of Macadamia integriflora extracts as antibacterial food agents
TLDR
The lack of toxicity of the M. integriflora extracts and their inhibitory bioactivity against a panel of bacteria and fungi demonstrate their potential as food additives to inhibit bacterial spoilage and food borne illnesses without the need for chemical preservative additives.
Evaluation of the antibacterial activity and toxicity of Terminalia ferdinandia fruit extracts
TLDR
The low toxicity of the T.Ferdinandiana extracts and their inhibitory bioactivity against bacteria validate australian aboriginal usage of T. ferdinandiana and indicates its medicinal potential as well as its potential as a source of natural ascorbic acid.
Comprehensive scientific demystification of Kigelia africana: A review
TLDR
This work represents the recent profile of applications of K. africana as examined by various modern scientific researches and indicates its status as a viable medicinal plant.
ANTIINFLAMMATORY ACTIVITY OF THE FRUIT OF Kigelia pinnata DC
TLDR
The results gave a scientific basis to the traditional uses of K.pinnata particularly involved in inflammation, and revealed the presence of flavonoids, carbohydrates, glycosides, proteins and alkaloids.
Gas chromatography-mass spectroscopy analysis of bioactive petalostigma extracts: Toxicity, antibacterial and antiviral activities
TLDR
These studies validate Australian Aboriginal therapeutic usage of Petalostigma species and indicate their medicinal potential.
...
1
2
3
4
5
...